반응 #48079

반응 방정식

4-bromo-1-chloro-2-isopropylbenzene

3-(4-tert-butylbenzyl)-[1,2,3]oxathiazolidine 2,2-dioxide

→

desired product

수율 42.2%

(4-tert-butylbenzyl)-[2-(4-chloro-3-isopropylphenyl)-ethyl]-amine

수율 42.2%

반응 조건

후처리

1. 1
   기타The residue was purified by flash column chromatography

실험 절차

The title compound was synthesized in analogy to example S6-C using 4-bromo-1-chloro-2-isopropylbenzene (120 mg, 0.51 mmol), and 3-(4-tert-butylbenzyl)-[1,2,3]oxathiazolidine 2,2-dioxide (138 mg, 0.51 mmol). The residue was purified by flash column chromatography to give the desired product (74 mg, 42%) as a light yellow oil. MS (ISP) 344.3 (M+H)+.

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