반응 #480311

반응 방정식

methacryloyl chloride

methacrylate

1,1,1-trifluoro-2-trifluoromethyl-2,4-pentanediol

n-butyllithium

→

title compound

1,1,1-trifluoro-2-trifluoromethyl-2-hydroxy-4-pentyl Methacrylate

반응 조건

후처리

1. 1
   기타to yield
2. 2
   workup.DISTILLATIONafter distillation at 67° C. at 1.0 mm Hg, 142 g (76%) of the 2° methacrylate as a clear, colorless oil

실험 절차

The title compound was prepared in the same fashion as the above described methacrylate using 142 g (0.63 mol) of 1,1,1-trifluoro-2-trifluoromethyl-2,4-pentanediol, 793 mL (1.27 mol) of n-butyllithium (1.6M in hexane) and 73 g (0.69 mol) of methacryloyl chloride to yield, after distillation at 67° C. at 1.0 mm Hg, 142 g (76%) of the 2° methacrylate as a clear, colorless oil.

출처