반응 #48004

반응 방정식

(2-aminoindan-2-yl)methanol

phthalic anhydride

→

2-(2-hydroxymethylindan-2-yl)-isoindole-1,3-dione

용매

water

반응 조건

후처리

1. 1
   추출extracted with chloroform
2. 2
   건조The organic phase is dried (Na2SO4)
3. 3
   기타evaporated

실험 절차

A mixture of (2-aminoindan-2-yl)methanol (0.407 g, 2.50 mmol) and phthalic anhydride (0.369 g, 2.50 mmol) is heated at 160° C. for 40 minutes. The reaction mixture is poured into water and extracted with chloroform. The organic phase is dried (Na2SO4) and evaporated to afford 2-(2-hydroxymethylindan-2-yl)-isoindole-1,3-dione, MH+294.

출처