반응 #47928

ord-08369462b61f4121b5919fa794c65df0

반응 방정식

CC(C)(C)c1ccc(Nc2ncnc3c2CNCC3)cn1
(5,6,7,8-tetrahydro-pyrido[4,3-d]pyrimidin-4-yl)-(6-tert-butyl-pyridin-3-yl)-amine
Clc1cccnc1Cl
2,3-dichloropyridine
CC(C)(C)c1ccc(Nc2ncnc3c2CN(c2ncccc2Cl)CC3)cn1
desired compound
CC(C)(C)c1ccc(Nc2ncnc3c2CN(c2ncccc2Cl)CC3)cn1
(6-tert-Butyl-pyridin-3-yl)-[6-(3-chloro-pyridin-2-yl)-5,6,7,8-tetrahydro-pyrido[4,3-d]pyrimidin-4-yl]-amine

반응 조건

상세 조건
See reaction.notes.procedure_details.

후처리

  1. 1
    기타The title compound was prepared

실험 절차

The title compound was prepared according to the procedure given for Compound 1C by reacting (5,6,7,8-tetrahydro-pyrido[4,3-d]pyrimidin-4-yl)-(6-tert-butyl-pyridin-3-yl)-amine with 2,3-dichloropyridine to give the desired compound as an off-white powder.

출처

DOI: 10.6084/m9.figshare.5104873.v1특허: US07745451B2uspto-grants-2010_06