반응 #47744

반응 방정식

arecoline hydrochloride

HCl

→

product

수율 46.0%

Arecaidine hydrochloride

수율 46.0%

용매

ethanol

반응 조건

후처리

1. 1
   기타In a 250 ml flask equipped with a magnetic stirrer and a condenser
2. 2
   온도at reflux for 6 hours
3. 3
   기타The solvents are evaporated off under reduced pressure
4. 4
   기타leaving a solid residue
5. 5
   기타The residue is recrystallized from a 95% ethanol/ether mixture in order

실험 절차

In a 250 ml flask equipped with a magnetic stirrer and a condenser, arecoline hydrochloride (4 g; 20.9 mmol) is added to a solution of 50 ml of 95% ethanol and 60 ml of concentrated HCl. The mixture is heated at 100° C. for 12 hours then at reflux for 6 hours. The solvents are evaporated off under reduced pressure leaving a solid residue. The residue is recrystallized from a 95% ethanol/ether mixture in order to produce 1.69 g of product (Yield=46%) in the form of white crystals.

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