반응 #47725

반응 방정식

N2,4-dip-tolylpyridine-2,3-diamine

2-(ethoxymethylene)malonnitrile

→

3,7-dip-tolyl-3H-imidazo[4,5-b]pyridine

수율 84.0%

용매

isopropanol

반응 조건

후처리

1. 1
   온도refluxed for 6 hours
2. 2
   기타The solution was removed
3. 3
   기타was purified
4. 4
   기타to thereby produce a solid crystalline product at a yield of 84%

실험 절차

0.70 mol of N2,4-dip-tolylpyridine-2,3-diamine and 2.56 mol of 2-(ethoxymethylene)malonnitrile were added in 10 ml of isopropanol, and refluxed for 6 hours. The solution was removed and was purified by using column chromatography to thereby produce a solid crystalline product at a yield of 84%.

출처