반응 #474164

ord-054b724107a040a58bde5d38a3801ed1

반응 조건

상세 조건
See reaction.notes.procedure_details.

후처리

  1. 1
    기타The final colorless mixture was evaporated to dryness at 100° C. under 2 mbar for 2 h

실험 절차

A mixture of 11.74 g of (3-(trimethoxysilyl)propyl)amine (0.0654 mol) and of 9.9 g of diisopropylcarbodiimide (0.0785 mol, 20% excess) was heated for 6 h 30 min at 80° C. Analysis by GC then showed an amine conversion of greater than 97%. The final colorless mixture was evaporated to dryness at 100° C. under 2 mbar for 2 h to give 22.5 g of a colorless, low-viscosity liquid corresponding to the expected guanidine.

출처

DOI: 10.6084/m9.figshare.5104873.v1특허: US08372935B2uspto-grants-2013_02