반응 #473214

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2-amino-5-[2,6-difluoro-4-(1-hydroxy-1-methylethyl)phenyl]thiophene-3-carboxamide

4-(6-chloro-2-methylpyridin-3-yl)-2-methylbut-3-yn-2-ol

→

title compound

5-[2,6-Difluoro-4-(1-hydroxy-1-methylethyl)phenyl]-2-{[5-(3-hydroxy-3-methylbut-1-yn-1-yl)-6-methylpyridin-2-yl]amino}thiophene-3-carboxamide

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실험 절차

The title compound was prepared as described in Example 1 using 2-amino-5-[2,6-difluoro-4-(1-hydroxy-1-methylethyl)phenyl]thiophene-3-carboxamide (100 mg, 0.32 mmol) and 4-(6-chloro-2-methylpyridin-3-yl)-2-methylbut-3-yn-2-ol (67 mg, 0.32 mmol) as starting materials.

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