반응 #4724

반응 방정식

Hydrogen peroxide

N-methyl-N'-[3-[3-(1-piperidinylmethyl)phenoxy]propyl]-1,2-hydrazine dicarbothioamide

→

N-Methyl-N'-[3-[3-(1-piperidinylmethyl)phenoxy]propyl]1,3,4-thiadiazole-2,5-diamine

용매

ethanol

반응 조건

후처리

1. 1
   온도the reaction mixture is briefly heated to boiling
2. 2
   여과The sulphur which separates is filtered off hot with the aid of active charcoal
3. 3
   농축the filtrate is concentrated by evaporation
4. 4
   기타purified by preparative layer chromatography

실험 절차

2 ml of 30% Hydrogen peroxide are added to 1.58 g (4 mmol) of N-methyl-N'-[3-[3-(1-piperidinylmethyl)phenoxy]propyl]-1,2-hydrazine dicarbothioamide in 30 ml of ethanol and the reaction mixture is briefly heated to boiling. The sulphur which separates is filtered off hot with the aid of active charcoal and the filtrate is concentrated by evaporation and purified by preparative layer chromatography.

출처