반응 #47173

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(2-Amino-5-chloro-phenyl)-phenyl-methanone

4-methoxy-benzenesulfonyl chloride

→

N-(2-Benzoyl-4-chloro-phenyl)-4-methoxy-benzenesulfonamide

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후처리

1. 1
   기타The known compound was prepared
2. 2
   기타purified by flash chromatography (20% EtOAc.Hexane)

실험 절차

The known compound was prepared according to the general procedure for the synthesis of N-Aryl-benzenesulfonamides previously described using (2-Amino-5-chloro-phenyl)-phenyl-methanone and 4-methoxy-benzenesulfonyl chloride and purified by flash chromatography (20% EtOAc.Hexane). 1H NMR (CDCl3) δ 9.63 (s, 1H) 7.75 (d, J=12 Hz, 1H) 7.57 (m, 3H) 7.49-7.35 (m, 5H) 7.33 (d, J=4 Hz, 1H) 6.69 (d, J=12 Hz, 2H) 3.67 (s, 3H). MS: m/z=402.0 (M++1).

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