반응 #47168

ord-c283994b4e15486abaa57cea0e2ef7d8

반응 방정식

Nc1ccc(Br)cc1C(=O)c1ccccc1
(2-Amino-5-bromo-phenyl)phenyl-methanone
COc1ccc(S(=O)(=O)Cl)cc1
4-Methoxy-benzenesulfonyl chloride
COc1ccc(S(=O)(=O)Nc2ccc(Br)cc2C(=O)c2ccccc2)cc1
title compound
COc1ccc(S(=O)(=O)Nc2ccc(Br)cc2C(=O)c2ccccc2)cc1
N-(2-Benzoyl-4-bromo-phenyl)-4-methoxy-benzenesulfonamide

반응 조건

상세 조건
See reaction.notes.procedure_details.

실험 절차

The title compound was prepared according to the general procedure for the synthesis of N-Aryl-benzenesulfonamides previously described using 138 mg of (2-Amino-5-bromo-phenyl)phenyl-methanone and 103 mg of 4-Methoxy-benzenesulfonyl chloride. 1H-NMR (400 MHz, CDCl3): δ 3.78 (s, 3H), 6.83 (d, 2H, J=9.2 Hz), 7.39 (b, 1H), 7.49 (d, 2H, J=6.4 Hz), 7.68 (m, 4H), 8.85 (d, 2H, J=6.0 Hz), 9.96 (b, 1H). MS: m/z 447.0 (M++1).

출처

DOI: 10.6084/m9.figshare.5104873.v1특허: US07741519B2uspto-grants-2010_06