반응 #470424

반응 방정식

4′,7-Dihydroxy-4-(4-methoxyphenyl)isoflav-3-ene

ethanol

4-Chlorobenzylamine

formaldehyde

→

title compound

수율 30.0%

4-(3-(4-Chlorobenzyl)-6-(4-methoxyphenyl)-2,3,4,8-tetrahydro-chromeno[6,7-e][1,3]oxazin-7-yl)phenol

수율 30.0%

반응 조건

후처리

1. 1
   기타The resulting precipitate was collected

실험 절차

4′,7-Dihydroxy-4-(4-methoxyphenyl)isoflav-3-ene (205 mg, 0.59 mmol) was dissolved in ethanol (1 ml). 4-Chlorobenzylamine (0.09 ml, 0.74 mmol) was added followed by formaldehyde solution (0.6 ml, 8.06 mmol, 37% wt.). The reaction stirred at room temperature for 3 days. The resulting precipitate was collected to afford the title compound (90 mg, 30%).

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