반응 #470419

반응 방정식

4′,7-Dihydroxyisoflav-3-ene

ethanol

4-Chlorobenzylamine

formaldehyde

→

title compound

수율 88.0%

4-(3-(4-Chlorobenzyl)-2,3,4,8-tetrahydrochromeno[6,7-e][1,3]oxazin-7-yl)phenol

수율 88.0%

반응 조건

후처리

1. 1
   기타The white precipitate was collected

실험 절차

4′,7-Dihydroxyisoflav-3-ene (506 mg, 2.11 mmol) was dissolved in ethanol (8 ml). 4-Chlorobenzylamine (0.33 ml, 2.70 mmol) was added followed by formaldehyde solution (2 ml, 0.03 mol, 37% wt.). The reaction was stirred at room temperature for 4 days. The white precipitate was collected to afford the title compound (748 mg, 88%).

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