반응 #470418

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7-Hydroxy-3′,4′-dimethoxy-8-methylisoflav-3-ene

ethanol

Benzylamine

formaldehyde

→

title compound

수율 15.0%

3-Benzyl-7-(3,4-dimethoxyphenyl)-10-methyl-2,3,4,8-tetrahydro-chromeno[6,7-e][1,3]oxazine

수율 15.0%

반응 조건

후처리

1. 1
   기타The precipitate was collected

실험 절차

7-Hydroxy-3′,4′-dimethoxy-8-methylisoflav-3-ene (155 mg, 0.52 mmol) was dissolved in ethanol (2.5 ml). Benzylamine (0.07 ml, 023 mmol) was added followed by formaldehyde solution (0.6 ml, 8.06 mmol, 37% wt.). The reaction was stirred at room temperature for 2 days. The precipitate was collected to afford the title compound (33 mg, 15%).

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