반응 #470396

반응 방정식

N-(2-nitrophenyl)biphenyl-2-amine

hydrogen

→

N1-(biphenyl-2-yl)benzene-1,2-diamine

용매

ethanol

반응 조건

후처리

1. 1
   여과The solution was filtered through Celite
2. 2
   기타to remove the catalyst, Celite
3. 3
   세척was washed with dichloromethane
4. 4
   기타the filtrate was evaporated
5. 5
   기타to yield a brown oil, 14.8 g (84%)
6. 6
   기타The product was used for the next step without further purification

실험 절차

N-(2-nitrophenyl)biphenyl-2-amine (19.69 g, 67.8 mmol), 10% palladium on carbon (0.29 g, 0.27 mmol), and 150 mL of ethanol was added to a Parr hydrogenator bottle. The mixture was hydrogenated on a Parr hydrogenator until no more hydrogen was taken up by the solution. The solution was filtered through Celite to remove the catalyst, Celite was washed with dichloromethane, the filtrate was evaporated to yield a brown oil, 14.8 g (84%). The product was used for the next step without further purification.

출처