반응 #470387

반응 방정식

N1-phenylbenzene-1,2-diamine

benzaldehyde

→

desired product

수율 37.0%

1,2-diphenyl-1H-benzo[d]imidazole

수율 37.0%

용매

methoxylethanol

반응 조건

후처리

1. 1
   온도The mixture was heated up
2. 2
   온도to reflux for 48 hours
3. 3
   기타the solvent was evaporated
4. 4
   기타The residue was purified by column chromatography

실험 절차

N1-phenylbenzene-1,2-diamine (4.15 g, 22 mmol) and benzaldehyde (2.1 g, 20 mmol) were mixed with methoxylethanol (60 ml) in a three-neck flask. The mixture was heated up to reflux for 48 hours. After cooled to room temperature, the solvent was evaporated. The residue was purified by column chromatography using dichloromethane to 5% of ethyl acetate in dichloromethane as eluent. 2 g of desired product was obtained.

출처