반응 #470374

반응 방정식

N-propylpyrrolidine

chloromethyl ethyl ether

→

white solid

N-Ethoxymethyl-N-Propylpyrrolidinium Chloride

용매

acetone

water

반응 조건

후처리

1. 1
   기타whereby the reaction was terminated
2. 2
   여과The reaction mixture was filtered
3. 3
   세척washed with 100 g of acetone
4. 4
   기타dried in a vacuum

실험 절차

A 36.22 g quantity of N-propylpyrrolidine was dissolved in 200 g of dehydrated acetone (up to 0.1% in water content), followed by replacement with nitrogen. To the solution was added dropwise 30.25 g of chloromethyl ethyl ether (reagent, product of Tokyo Kasei Co., Ltd. as purified by distillation) at 5° C. over a period of 1 hour. The mixture was stirred at 5° C. for 5 hours, whereby the reaction was terminated. The reaction mixture was filtered, washed with 100 g of acetone and dried in a vacuum, giving 53.30 g of a white solid product.

출처