반응 #470368

반응 방정식

sodium acetate

N-methoxymethyl-N-methylpyrrolidinium chloride

N-Methyl-N-Methoxymethylpyrrolidinium Chloride

→

desired product

N-Methoxymethyl-N-Methylpyrrolidinium Acetate

용매

methanol

반응 조건

후처리

1. 1
   기타The mixture was reacted at room temperature for 1.5 hours
2. 2
   기타whereby the reaction was terminated
3. 3
   여과The reaction mixture was filtered
4. 4
   농축the filtrate was concentrated
5. 5
   기타dried in a vacuum
6. 6
   workup.ADDITIONTo the residue was added 100 ml of dichloromethane
7. 7
   여과followed by filtration with a membrane
8. 8
   여과filter
9. 9
   농축concentration in a vacuum
10. 10
    기타drying

실험 절차

A 9.46 g quantity of sodium acetate (product of Wako Pure Chemical Ind. Ltd.) was dissolved in 95 g of methanol, and 19.10 g of N-methoxymethyl-N-methylpyrrolidinium chloride was added to the solution. The mixture was reacted at room temperature for 1.5 hours, whereby the reaction was terminated. The reaction mixture was filtered, and the filtrate was concentrated and dried in a vacuum. To the residue was added 100 ml of dichloromethane, followed by filtration with a membrane filter, concentration in a vacuum and drying, affording 20.38 g of the desired product.

출처