반응 #470366

반응 방정식

potassium fluoride

N-methoxymethyl-N-methylpyrrolidinium perchlorate

→

desired product

N-Methoxymethyl-N-Methylpyrrolidinium Fluoride

용매

water

반응 조건

후처리

1. 1
   기타The mixture was reacted at room temperature for 1.5 hours
2. 2
   기타whereby the reaction was terminated
3. 3
   workup.ADDITIONWith addition of 100 ml of methanol
4. 4
   여과the reaction mixture was filtered
5. 5
   농축The filtrate was concentrated
6. 6
   기타dried in a vacuum
7. 7
   workup.DISSOLUTIONThe residue was then dissolved in dichloromethane
8. 8
   여과the solution was again filtered with a membrane
9. 9
   여과filter
10. 10
    농축the filtrate was concentrated
11. 11
    기타dried

실험 절차

A 0.44 g quantity of potassium fluoride (product of Wako Pure Chemical Ind. Ltd.) was dissolved in 11 g of deionized water, and 1.74 g of N-methoxymethyl-N-methylpyrrolidinium perchlorate was added to the solution. The mixture was reacted at room temperature for 1.5 hours, whereby the reaction was terminated. With addition of 100 ml of methanol, the reaction mixture was filtered. The filtrate was concentrated and dried in a vacuum. The residue was then dissolved in dichloromethane, the solution was again filtered with a membrane filter, and the filtrate was concentrated and dried, giving 1.05 g of the desired product.

출처