반응 #47000

반응 방정식

cis-4,5-bis-(2-bromophenyl)imidazolidine-2-thione

cis-4,5-bis-(2-Bromophenyl)imidazolidine-2-thione

methyl iodide

→

product 52

수율 67.7%

cis-4,5-bis-(2-Bromophenyl)-2-methylthio-4,5-dihydro-1H-imidazole hydroiodide

수율 67.7%

용매

EtOH

반응 조건

후처리

1. 1
   농축concentrated in vacuo
2. 2
   여과The insoluble material is filtered

실험 절차

A solution of cis-4,5-bis-(2-bromophenyl)imidazolidine-2-thione (35) (0.51 g, 1.36 mmol) and methyl iodide (0.178 mL, 2.1 mmol) in abs. EtOH (20 mL) is heated at 90° C. overnight. The reaction mixture is cooled to rt, concentrated in vacuo, and the residue suspended in Et2O. The insoluble material is filtered to give 0.51 g of the product 52.

출처