반응 #46786

반응 방정식

4-Chloro-phenylamine

pyridine

bromo-acetyl bromide

→

2-Bromo-N-(4-Chloro-phenyl)-acetamide

용매

toluene

toluene

반응 조건

후처리

1. 1
   workup.ADDITIONwere added dropwise under ice cooling
2. 2
   기타After 2 h the precipitate was isolated by filtration
3. 3
   기타recrystallized from toluene
4. 4
   기타to yield a white solid

실험 절차

To a solution of 5 g 4-Chloro-phenylamine and 1.5 mL pyridine in 30 mL toluene, 8 g bromo-acetyl bromide dissolved in 10 mL toluene were added dropwise under ice cooling. After 2 h the precipitate was isolated by filtration and recrystallized from toluene to yield a white solid.

출처