반응 #467428

ord-c32f031be860421294511432fc30871b

용매

반응 조건

상세 조건
See reaction.notes.procedure_details.

후처리

  1. 1
    기타Into a 1 liter round bottom flask equipped with an addition funnel and a reflux condenser
  2. 2
    온도to maintain a refluxing solution
  3. 3
    기타was consumed
  4. 4
    기타This process produced a solution

실험 절차

Into a 1 liter round bottom flask equipped with an addition funnel and a reflux condenser were placed magnesium turnings (24.3 g, 1.0 mol), diisopropylamine (20.2 g, 0.2 mol) and THF (500 ml). Bromoethane (120.0 g, 1.1 mol) was added dropwise to this mixture via the addition funnel at such a rate as to maintain a refluxing solution. Ethane was evolved during the addition. The reaction was determined to be complete once all of the magnesium was consumed. This process produced a solution containing EtMgBr and DAMB.

출처

DOI: 10.6084/m9.figshare.5104873.v1특허: US06303057B1uspto-grants-2001_10