반응 #467029

ord-e00bc63b49e04c96963ad60b9fdd0fc6

반응 방정식

CC1CCCC(C(=O)c2[nH]c3cc(Cl)ccc3c2N)C1
3-amino-6-chloro-2-(3-methylcyclohexylcarbonyl)indole
CC(=O)Cl
acetyl chloride
→
CC(=O)Nc1c(C(=O)C2CCCC(C)C2)[nH]c2cc(Cl)ccc12
title compound
CC(=O)Nc1c(C(=O)C2CCCC(C)C2)[nH]c2cc(Cl)ccc12
3-Acetylamino-6-chloro-2-(3-methylcyclohexylcarbonyl)indole

반응물

CC1CCCC(C(=O)c2[nH]c3cc(Cl)ccc3c2N)C1
3-amino-6-chloro-2-(3-methylcyclohexylcarbonyl)indole
CC(=O)Cl
acetyl chloride

시약

없음

용매

CCCCCC.CCOC(C)=O
ethyl acetate hexane

반응 조건

상세 조건
See reaction.notes.procedure_details.

실험 절차

The title compound was prepared according to the procedure described in Example 19 employing 3-amino-6-chloro-2-(3-methylcyclohexylcarbonyl)indole (Example 144) and acetyl chloride. m.p.: 202-203° C. (ethyl acetate/hexane)

출처

DOI: 10.6084/m9.figshare.5104873.v1특허: US06300363B1uspto-grants-2001_10