반응 #465050
ord-7e9413f597074816812d10d8ad9a712d
반응 방정식
반응 조건
상세 조건
See reaction.notes.procedure_details.
후처리
- 1농축The mixture was concentrated under the reduced pressure
- 2기타to remove tetrahydrofuran
- 3기타purified by column chromatography(hexane:ether=5:1)
실험 절차
Phenyl N-(2-methoxyquinolin-3-yl)carbamate(148 mg, 0.5 mmol) and 1-(3,5-dimethoxyphenyl)piperazine(112 mg, 0.5 mmol) were dissolved in anhydrous tetrahydrofuran and DBU(117 mg, 0.75 mmol) was added. The solution was stirred at room temperature for 2 hours. The mixture was concentrated under the reduced pressure to remove tetrahydrofuran and purified by column chromatography(hexane:ether=5:1) to obtain the titled compound.