반응 #465049

반응 방정식

3-Amino-2-methoxyquinoline

phenyl chloroformate

→

titled compound

수율 75.0%

Phenyl N-(2-methoxyquinolin-3-yl)carbamate

수율 75.0%

용매

dichloromethane

반응 조건

후처리

1. 1
   농축The above mixture was concentrated under the reduced pressure
2. 2
   기타to remove dichloromethane
3. 3
   기타purified by column chromatography(hexane:ether=8:1)

실험 절차

3-Amino-2-methoxyquinoline(4 g, 23 mmol) and phenyl chloroformate(4.04 g, 25 mmol) were dissolved in dichloromethane and stirred at room temperature for 2 hours. The above mixture was concentrated under the reduced pressure to remove dichloromethane and purified by column chromatography(hexane:ether=8:1) to obtain the titled compound.

출처