반응 #4636
ord-2158019772d240b48c99ecea1fc7c2f3
반응 조건
상세 조건
See reaction.notes.procedure_details.
후처리
- 1온도is refluxed
- 2여과The reaction mixture is filtered
- 3온도whilst still warm
- 4농축the filtrate concentrated by evaporation
- 5기타the residue recrystallised from a little methanol
실험 절차
A mixture of 23.0 g of 2,6-dihydroxybenzamide, 20.7 g of potassium carbonate and 28.2 g of 1,2-dibromoethane is refluxed, whilst stirring, for 2-3 hours in 300 ml of acetonitrile. The reaction mixture is filtered whilst still warm, the filtrate concentrated by evaporation and the residue recrystallised from a little methanol. 6-(2-Bromoethoxy)salicylamide having a melting point of 120°-121° is obtained.