반응 #46320

반응 방정식

HCl

compound

(±)-cis 1-Hydroxy-6-methoxy-3,3,14-trimethyl-7-oxo-2,3,7,14-tetrahydro-1H-benzo[b]chromeno[6,5-g][1,8]naphthyridin-2-yl butyrate

→

6-Methoxy-3,3,14-trimethyl-7-oxo-7,14-dihydro-3H-benzo[b]chromeno[6,5-g][1,8]naphthyridin-2-yl butyrate

용매

dichloromethane

반응 조건

후처리

1. 1
   기타dried
2. 2
   농축concentrated under reduced pressure
3. 3
   기타to be isolated

실험 절차

Add 4 drops of a 10% solution of HCl to a solution of 0.29 mmol of the compound of Example 13 in 6 ml of dichloromethane. The reaction mixture is stirred for 3 days at ambient temperature and then dried and concentrated under reduced pressure. Chromatography of the residue on silica gel (dichloromethane/methanol gradient) allows the expected product to be isolated.

출처