반응 #462537

반응 방정식

5,6-diamino-1,3-diethyluracil

4-fluorocinnamic acid

→

Compound 146

수율 51.0%

(E)-1,3-Diethyl-8-(4-fluorostyryl)xanthine

수율 51.0%

반응 조건

후처리

1. 1
   기타Then, the resultant crude crystals were recrystallized from tetrahydrofuran/water

실험 절차

Substantially the same procedure as in Example 7 was repeated using 2.50 g (12.6 mmol) of 5,6-diamino-1,3-diethyluracil and 2.31 g (13.9 mmol) of 4-fluorocinnamic acid. Then, the resultant crude crystals were recrystallized from tetrahydrofuran/water to give 2.00 g (yield 51%) of Compound 146 as colorless columns.

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