반응 #459822

반응 방정식

methylamine

product

4,6-dichloro-2-methylamino-5-pyrimidinecarbonitrile

4,6-dichloro-2-methylamino-5-pyrimidinecarbonitrile

2,4-dichloro-6-methylamino-5-pyrimidinecarbonitrile

→

4-chloro-2,6-bis(methylamino)-5-pyrimidinecarbonitrile

반응 조건

실험 절차

The crude reaction product of Example IX, approximately 19% 4,6-dichloro-2-methylamino-5-pyrimidinecarbonitrile and 72% 2,4-dichloro-6-methylamino-5-pyrimidinecarbonitrile, was treated with aqueous 40% methylamine in the manner of Example V, to give 4-chloro-2,6-bis(methylamino)-5-pyrimidinecarbonitrile; mp, 281°-284° C.

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