반응 #4583

반응 방정식

3-chloroperbenzoic acid

2-allyloxyphenylsulfonamide

→

2-oxiranylmethoxyphenylsulfonamide

수율 78.0%

용매

methylene chloride

반응 조건

후처리

1. 1
   온도The solution is then heated
2. 2
   온도to reflux for 3 hours
3. 3
   온도cooled
4. 4
   세척washed three times with saturated sodium carbonate solution
5. 5
   기타The organic phase is dried
6. 6
   농축concentrated

실험 절차

To a mixture of 15.3 g of 3-chloroperbenzoic acid in 270 ml of absolute methylene chloride are added 14.2 g of 2-allyloxyphenylsulfonamide over 2 minutes. The solution is then heated to reflux for 3 hours, cooled, and then washed three times with saturated sodium carbonate solution and once with water. The organic phase is dried and concentrated, affording 11.9 g of 2-oxiranylmethoxyphenylsulfonamide with a melting point of 132°-133° C.

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