반응 #4577

반응 방정식

methyl 5-chlorooxindole-3-carboxylate

phenylisocyanate

→

Methyl 1-N-(phenyl)carbamoyl-5-chlorooxindole-3-carboxylate

용매

toluene

—

petroleum ether

반응 조건

후처리

1. 1
   온도heated
2. 2
   온도to reflux overnight
3. 3
   온도The reaction mixture was cooled
4. 4
   기타to give
5. 5
   여과after filtration
6. 6
   기타drying

실험 절차

To 6.0 g. (0.027 mole) of methyl 5-chlorooxindole-3-carboxylate in 200 ml. of toluene was added 5.25 ml. (0.048 mole) of phenylisocyanate and the resulting reaction mixture heated to reflux overnight. The reaction mixture was cooled and diluted with petroleum ether to give, after filtration and drying, 2.0 g. of the desired product.

출처