반응 #452424

반응 방정식

N-(4-fluorobenzoyl)-4-nitroaniline

→

N-(4-fluoro-benzoyl)-4-aminoaniline

수율 79.0%

용매

tetrahydrofuran

반응 조건

후처리

1. 1
   여과The reaction mixture was then filtered
2. 2
   농축the filtrate concentrated under reduced pressure

실험 절차

A mixture of 32.25 gm (124 mMol) N-(4-fluorobenzoyl)-4-nitroaniline and 3.2 gm platinum on carbon in 500 mL tetrahydrofuran was hydrogenated at room temperature for 18 hours with an initial pressure of 60 p.s.i. The reaction mixture was then filtered and the filtrate concentrated under reduced pressure to give 22.45 gm (79%) of N-(4-fluoro-benzoyl)-4-aminoaniline.

출처