반응 #452273

반응 방정식

Furo[2,3-b]pyridine-5,6-dicarboxylic acid

→

furo[2,3-b]pyridine-5,6-dicarboxylic acid anhydride

수율 88.4%

용매

acetic anhydride

반응 조건

후처리

1. 1
   농축concentrated in vacuo
2. 2
   기타the residue triturated with cyclohexane-ether (5:1)
3. 3
   여과filtered off
4. 4
   기타dried

실험 절차

Furo[2,3-b]pyridine-5,6-dicarboxylic acid (6.7 g, 0.032 mol) is heated at 60° C. for 30 minutes in acetic anhydride (150 mL). The reaction mixture is cooled to room temperature and concentrated in vacuo and the residue triturated with cyclohexane-ether (5:1), filtered off and dried to give 5.35 g furo[2,3-b]pyridine-5,6-dicarboxylic acid anhydride.

출처