반응 #452154

반응 방정식

2-(n-butylamino)ethanol

ethyl chloroformate

→

ethyl (2-hydroxyethyl)-n-butylcarbamate

용매

methylene chloride

반응 조건

후처리

1. 1
   기타to drop in during 1 hour at 30°-35° C. with ice-
2. 2
   온도cooling
3. 3
   기타the methylene chloride is evaporated
4. 4
   workup.DISTILLATIONthe residue is distilled

실험 절차

117.2 g of 2-(n-butylamino)ethanol and placed in 300 ml of methylene chloride. Then 54.3 g of ethyl chloroformate are allowed to drop in during 1 hour at 30°-35° C. with ice-cooling. After stirring for an additional 2 hours, the methylene chloride is evaporated and the residue is distilled to yield pure ethyl (2-hydroxyethyl)-n-butylcarbamate; b.p. 112° C./0.1 Torr.

출처