반응 #4521

반응 방정식

tert-butanol

α-chloroethyl chloroformate

pyridine

→

α-chloroethyl tert-butyl carbonate

용매

dicloromethane

반응 조건

후처리

1. 1
   온도In a reactor cooled to +5° C.
2. 2
   온도is maintained at between 10° and 20° C
3. 3
   workup.STIRRINGThe mixture is stirred for 4 hours at room temperature

실험 절차

In a reactor cooled to +5° C., there are introduced 600 ml of dicloromethane, 43.7 g (0.59 mole) of tert-butanol and 94.7 g (0.66 mole) of α-chloroethyl chloroformate. 57 g (0.72 mole) of pyridine are then added dropwise and with stirring while the temperature is maintained at between 10° and 20° C. The mixture is stirred for 4 hours at room temperature.

출처