반응 #452047
ord-f554fae2117845d8b92c170acb3ca7e2
반응 방정식
triethanolamine
methylamine hydrochloride
3-carboxymethyl-5ethoxymethylidenerhodanine
→
3-carboxymethyl-5-methylaminomethylidenerhodanine methylamine salt
수율 79.2%
반응 조건
상세 조건
See reaction.notes.procedure_details.
후처리
- 1농축The reaction mixture was concentrated
- 2기타the resulting residue was recrystallized from ethanol
실험 절차
A mixture of 0.68 g (0.010 mole) of methylamine hydrochloride and 5 ml of ethanol, which was neutralized with 1.0 g (0.010 mole) of triethanolamine, was added to a mixture of 1.2 g (0.005 mole) of 3-carboxymethyl-5ethoxymethylidenerhodanine and 10 ml of ethanol. The reaction was conducted at a temperature of 50° to 60° C. for 1 hour. The reaction mixture was concentrated and the resulting residue was recrystallized from ethanol to give 1.0 g of 3-carboxymethyl-5-methylaminomethylidenerhodanine methylamine salt (yield: 79.2 %).