반응 #450366

반응 방정식

2-phenyl-5-methyl pyridine

potassium permanganate

water

→

2-Phenyl-5-carboxypyridine

반응 조건

후처리

1. 1
   온도at reflux for 2 hours
2. 2
   여과filtered through celite
3. 3
   기타to remove the solids
4. 4
   workup.ADDITIONAcetic acid (1 mL) was added to the colourless filtrate
5. 5
   여과the product was collected as a white solid by filtration

실험 절차

A suspension of 2-phenyl-5-methyl pyridine (1.03 g, 6.09 mmol) and potassium permanganate (2.89 g, 18.3 mmol), in water (25 mL) was heated at reflux for 2 hours. The reaction was allowed to cool to ambient temperature and filtered through celite to remove the solids. Acetic acid (1 mL) was added to the colourless filtrate and the product was collected as a white solid by filtration.

출처