반응 #450200

반응 방정식

4-(1,3-diphenyl-1-propoxy)benzyl bromide

4-aminopyridine

→

4-amino-1-[4-(1,3-diphenyl-1-propoxy)benzyl]pyridinium bromide

용매

acetonitrile

반응 조건

후처리

1. 1
   workup.STIRRINGThe mixture was stirred for 3 hrs
2. 2
   여과the resulting white suspension was filtered
3. 3
   기타The white solid obtained 6-8, melted at 215°-216.5° C
4. 4
   기타Recrystallization from acetonitrile
5. 5
   온도raised the melting point to 218.5°-220° C.

실험 절차

To a solution of 4-(1,3-diphenyl-1-propoxy)benzyl bromide 6-6 (0.381 g, 1.0 mmol) in acetonitrile (7 ml) was added 4-aminopyridine (6-7) (94 mg, 1.0 mmol) with stirring at room temperature. The mixture was stirred for 3 hrs and the resulting white suspension was filtered. The white solid obtained 6-8, melted at 215°-216.5° C. Recrystallization from acetonitrile raised the melting point to 218.5°-220° C.

출처