반응 #44974

반응 방정식

5-Aminovaleric acid

methanol

thionyl chloride

→

methyl 5-aminovalerate hydrochloride

반응 조건

후처리

1. 1
   온도cooling
2. 2
   농축The reaction solution is concentrated under reduced pressure
3. 3
   여과the precipitates are collected by filtration

실험 절차

5-Aminovaleric acid (7.35 g) is dissolved in methanol (50 ml), and thereto is added dropwise thionyl chloride (4.9 ml) under ice-cooling. The reaction solution is then warmed to room temperature and stirred for 17 hours. The reaction solution is concentrated under reduced pressure. The resulting residue is suspended in diethyl ether and the precipitates are collected by filtration to give methyl 5-aminovalerate hydrochloride (9.93 g).

출처