반응 #44841

반응 방정식

2-chlorobenzimidazole

7-fluoro-1,2,3,4-tetrahydro-1-naphthylamine

→

title compound

N-(Benzimidazol-2-yl)-7-fluoro-1,2,3,4-tetrahydro-1-naphthylamine

반응 조건

후처리

1. 1
   기타The product was purified by column chromatography

실험 절차

The title compound was prepared from 2-chlorobenzimidazole and 7-fluoro-1,2,3,4-tetrahydro-1-naphthylamine (prepared by Procedure B from 7-fluoro-1 -tetralone) by Procedure A. The product was purified by column chromatography to give the title compound as the free base and as a mixture of enantiomers (white solid, mp 181° C.). MS(ES+) m/z 282 ([M+1]+, 100).

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