반응 #44836

반응 방정식

2-chlorobenzimidazole

5 ,7-dimethyl-1,2,3,4-tetrahydro-1-naphthylamine

→

title compound

N-(Benzimidazol-2-yl)-5,7-dimethyl-1,2,3,4-tetrahydro-1-naphthylamine

반응 조건

후처리

1. 1
   기타The product was purified by recrystallisation

실험 절차

The title compound was prepared from 2-chlorobenzimidazole and 5 ,7-dimethyl-1,2,3,4-tetrahydro-1-naphthylamine (prepared by Procedure B from 5,7-dimethyl-1-tetralone) by Procedure A (60 min at 170° C. followed by 20 min at 200° C.). The product was purified by recrystallisation to give the title compound as the free base and as a mixture of enantiomers (white solid, mp 250-252° C.). MS(ES+) m/z 292 ([M+1]+, 100).

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