반응 #4473
ord-477e144581644ea4bec3777f5ed06716
반응 방정식
product
1,3-Cyclohexanedione mono(4-bromophenylhydrazone)
water
→
title compound
6-Bromo-1,2,3,9-tetrahydro-4H-carbazol-4-one
반응 조건
상세 조건
See reaction.notes.procedure_details.
후처리
- 1온도The mixture was cooled
- 2여과the resulting solid filtered off
- 3기타dried (0.95 g)
- 4기타Purification by flash chromatography (E)
실험 절차
The product of Stage (i) (1.5 g) was heated under reflux with dry zinc chloride (16 g) in glacial acetic acid (75 ml) for 24 h. The mixture was cooled, poured into water (200 ml), and the resulting solid filtered off and dried (0.95 g). Purification by flash chromatography (E) gave the title compound as a solid (125 mg). T.l.c. (F), Rf 0.65