반응 #44675

반응 방정식

3-amino-1,2-benzisoxazol-4-ol

3,4-difluoronitrobenzene

potassium carbonate

→

4-(2-Fluoro-4-nitrophenoxy)-1,2-benzisoxazole-3-amine

용매

dimethylformamide

water

반응 조건

후처리

1. 1
   여과the precipitate is filtered off
2. 2
   기타The product is dried under high vacuum

실험 절차

94.37 mg (0.63 mmol) of 3-amino-1,2-benzisoxazol-4-ol (from example V), 100 mg (0.63 mmol) of 3,4-difluoronitrobenzene and 95.56 mg (0.69 mmol) of potassium carbonate are suspended in 3 ml of anhydrous dimethylformamide and stirred at room temperature for 16 hours. The reaction solution is then diluted with water, and the precipitate is filtered off. The product is dried under high vacuum.

출처