반응 #445808

반응 방정식

1,8-dibromooctane

ethylisobutyrate

lithium diisopropylamide

→

title compound

수율 16.5%

Ethyl 2,2-Dimethyl-10-bromodecanoate

수율 16.5%

용매

hexamethylphosphoramide

반응 조건

실험 절차

Using the method described in Example 5(i), 1,8-dibromooctane (27.2 g, 0.1 mol) and ethylisobutyrate (10.44 g, 0.09 mol) were reacted in the presence of lithium diisopropylamide (67 ml, 0.1 mol) and hexamethylphosphoramide (22 g) to give the title compound (4.56 g) as an oil.

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