반응 #445801
ord-d5c0e32b8e5c4f339814a1b6d66005ad
반응 방정식
반응 조건
상세 조건
See reaction.notes.procedure_details.
후처리
- 1온도the resulting solution was heated
- 2온도at reflux for 3.5 hours
- 3온도The solution was cooled
- 4여과The precipitate was collected by filtration
- 5기타recrystallised from ethanol-water
실험 절차
Methyl 7-phthalimidohept-5-ynoate (1.45 g) was dissolved in a mixture of concentrated hydrochloric acid (7.3 ml), acetone (30 ml) and water (14.6 ml) and the resulting solution was heated at reflux for 3.5 hours. The solution was cooled and then poured into water (175 ml). The precipitate was collected by filtration and recrystallised from ethanol-water to give the title compound (1.12 g) m.p. 120°-122° C.