반응 #44347

반응 방정식

diethyl ether

water

product

[4-(methylthio)-3-(trifluoromethyl)phenyl]-boronic acid

pinacol

→

4,4,5,5-tetramethyl-2-[4-(methylthio)-3-(trifluoromethyl)phenyl]-1,3,2-dioxaborolane

용매

dioxan

반응 조건

후처리

1. 1
   기타The organic layer was separated
2. 2
   세척washed with brine
3. 3
   건조dried (Na2SO4)
4. 4
   농축concentrated in vacuo

실험 절차

The product of step b) (0.25 g) was heated in dioxan (2 ml) with pinacol (2 equiv) for 3 h. The solution was treated with diethyl ether and water. The organic layer was separated, washed with brine, dried (Na2SO4) and concentrated in vacuo. Yield 85 mg.

출처