반응 #44309

반응 방정식

methanol

biphenyl

4-chlorobenzenesulphonyl chloride

→

4-(4′-chlorobenzenesulphonyl)biphenyl

수율 65.0%

용매

trichlorobenzene

반응 조건

후처리

1. 1
   온도was heated
2. 2
   workup.STIRRINGstirring
3. 3
   여과The product was filtered
4. 4
   세척washed with methanol
5. 5
   기타dried
6. 6
   기타recrystallised from acetic acid

실험 절차

A mixture of biphenyl (10 g, 0.065 mol) and 4-chlorobenzenesulphonyl chloride (13.69 g, 0.065 mol) in trichlorobenzene (3 mL) was heated with stirring to 110° C. Anhydrous ferric chloride (0.05 g, 0.0003 mmol) was added and stirring was continued at 150° C. for 16 h. The cooled solid was stirred with methanol (200 mL). The product was filtered, washed with methanol, dried, and recrystallised from acetic acid to give 4-(4′-chlorobenzenesulphonyl)biphenyl (13.9 g, 65%); m.p. 169° C. (lit. 171-173° C.).

출처