반응 #439463

반응 방정식

2-propyl-5-fluoro-1,2,3,4-tetrahydro-6-naphthol

( 7-3 )

2-propyl-6-(3,4,5-trifluorophenyl)-1,2,3,4-tetrahydronaphthalene

→

2-propyl-7-fluoro-1,2,3,4-tetrahydro-6-naphthol

2-propyl-1,2,3,4-tetrahydro-6-naphthol

용매

( 7-2 )

2-propyl-1,2,3,4-tetrahydronaphthalen-6-yl trifluoromethanesulfonate

( 7-2 )

2-propyl-1,2,3,4-tetrahydronaphthalen-6-yl trifluoromethanesulfonate

반응 조건

실험 절차

Syntheses were performed in the same manner as (7-2) and (7-3), with the exception of using the 2-propyl-5-fluoro-1,2,3,4-tetrahydro-6-naphthol and the 2-propyl-7-fluoro-1,2,3,4-tetrahydro-6-naphthol obtained in (10-1) above instead of the 2-propyl-1,2,3,4-tetrahydro-6-naphthol in (7-2), and yielded 35 g of 2-propyl-5-fluoro-6-(3,4,5-trifluorophenyl)-1,2,3,4-tetrahydronaphthalene, and 53 g of 2-propyl-7-fluoro-6-(3,4,5-trifluorophenyl)-1,2,3,4-tetrahydronaphthalene respectively.

출처