반응 #43923
ord-fe0b5de1698444ec8b5a4db7374edae3
반응 방정식
ethyl 4-chloroacetoacetate
resorcinol
→
title compound
수율 84.0%
4-(chloromethyl)-7-hydroxy-2H-chromen-2-one
수율 84.0%
반응 조건
상세 조건
See reaction.notes.procedure_details.
후처리
- 1온도Under ice-cooling
- 2여과the precipitated solid was collected by filtration
- 3세척washed with water
- 4기타air-dried
실험 절차
Under ice-cooling, ethyl 4-chloroacetoacetate (14.0 g, 85.0 mmol) was dissolved in concentrated sulfuric acid (30 mL), resorcinol (8.81 g, 80.0 mmol) was added by small portions, and the mixture was stirred at room temperature for 2 hr. The reaction mixture was poured into ice water, and the precipitated solid was collected by filtration, washed with water, and air-dried to give the title compound (14.1 g, yield 84%) as a beige powder.