반응 #43886
ord-958f4ca71a0043ed81f947dbc750f7d2
용매
반응 조건
온도
27.5°CELSIUS
상세 조건
See reaction.notes.procedure_details.
후처리
- 1여과Filtered the solid
- 2세척washed with 30 ml of acetone
- 3기타dried
실험 절차
Oseltamivir tartrate (13 gm, obtained in example 3) is added to acetone (150 ml) at 25-30° C., the solution of H3PO4 (3.5 gm) in 40 ml of ethanol is added to the contents and then stirred for 1 hour 30 minutes at 25-30° C. Filtered the solid, washed with 30 ml of acetone and dried to yield 6.5 gm of oseltamivir phosphate (HPLC purity: 99.8%).